Necrotizing enterocolitis: a complication of prematurity. Its pathogenesis, prevention and management

Dr. Pradyumna Pan
Department Of Pediatric Surgery, India

Published on: 2019-11-23

Abstract

One of the most severe gastrointestinal illness that occur in newborns is neonatal necrotizing enterocolitis (NEC). This puzzling disease remains a challenge for neonatologists around the globe with uncertain definite etiology along with extremely high mortality and morbidity.

Keywords

Neonatal necrotizing enterocolitis, Low birth weight, Preterm, Complications, Managements.

NEC typically occurs in premature, formula-fed babies during the second to the fifth week of life. It is characterized by variable damage to the intestinal tract, ranging from mucosal injury to full-thickness necrosis and perforation. The risk is inversely proportional to gestational age and weight at birth. Paltauf first described the condition in 1888 but the term “necrotizing enterocolitis” was used for the first time by Schmid and Quaiser in 1953[1].

One of the most severe gastrointestinal illness that occur in newborns is neonatal necrotizing enterocolitis (NEC). This puzzling disease remains a challenge for neonatologists around the globe with uncertain definite etiology along with extremely high mortality and morbidity.