MedRead Journal of Cardiology Research

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Aortic dissection after sildenafi i use, a rare Cooccurence, case report of an autopsy

*Mehmet Saki Celik
Council Of Forensic Medicine Sakarya Branch Directorate, Turkey

*Corresponding Author:
Mehmet Saki Celik
Council Of Forensic Medicine Sakarya Branch Directorate, Turkey

Published on: 2020-03-17

Abstract

Aortic dissection is a disease with a high mortality rate. It is defined as the passage of blood from a rupture in the intimal layer to the medial layer of the aortic lumen. Sildenafil, which is used in the treatment of erectile dysfunction, has a vasorelaxant effect on the aorta. The use of sildenafil triggers aortic dissection. We have reported a patient who had no medical history other than a diagnosis of hypertension, and whose autopsy revealed aortic dissection and post-mortem blood examination revealed sildenafil.

 

 

 

Keywords

Sildenafil, Aortic Dissection, Cardiac Tamponade

Aortic Dissection After Sildenafi L Use, A Rare Cooccurence, Case Report Of An Autopsy

Aortic dissection is defined as the passage of blood from a rupture in the intimal layer to the medial layer in the aortic lumen. It is a life-threatening sudden onset condition that requires immediate diagnosis and treatment. Mortality rate is quite high despite the treatment. Dissection, especially in the ascending aorta, the mortality rate can be 25% in the fi rst 24 hours and 50% in the fi rst 48 hours from the onset of symptoms if left untreated.