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Clinical, dermoscopic and histopathological evaluation of giant histiocytofibroma

*Jihane Ziani
Departement Of Otolarygology, Hassan II Hospital University, Morocco

*Corresponding Author:
Jihane Ziani
Departement Of Otolarygology, Hassan II Hospital University, Morocco

Published on: 2020-04-09

Abstract

Benign histiocytofibroma (HFB) is one of the most common benign tumors, most commonly occurring in the lower limbs of adults, mostly women. It is often a small lesion, however there are atypical (HFB). Deep soft tissue and certain organs can also be affected. It mainly develops in the subcutaneous tissue. We report a case of and study its anatomo-clinical and dermoscopic aspect of this entity

Keywords

Dermoscopy; Pediculus corporis

Case Presentation

Observation: It is a 34-year-old patient, without notable pathological ATCD, who presents for 1 and a half years, a brown lesion, on the anterior aspect of the left leg non-painful non pruriginous, gradually increasing in size becoming in relief but functional signs. On clinical examination, we have note a nodule of 1 cm of erythematous mole consistency in places and pigmented by others, well limited, with regular contours, base not infiltrated, resting on healthy skin (Figure 1). The dermoscopic examination, in turn, objectified interspersed shiny white linear structures achieving a grid appearance, with the visualization of vessels in points at its crossed structures (Figure 2). The biopsy exeresis of the lesion objectified, a spindle cell population, a fasciculate and storiform architecture with polymorphonuclear cells, eosinophils and lymphocytes. In favor of a histiocytofibroma (Figure 3).
A benign dermatofibroma or histiocytofibroma is a firm papular or nodular lesion, most often small, reddish-brown in color, fibrohistiocytic in nature. They most often sit on the thighs or legs but they can sit anywhere. The is often clinical. The lesions are sometimes biopsied to exclude melanocytic proliferation or other tumors. In histology, we find spindle cells of small fibroblastic or pseudohistiocytic type with slightly angular nuclei are arranged in short crisscrossed bundles, accompanied by some histiocytes or multinucleated giant cells and a variable number of inflammatory cells [1].
The most common pattern associated with dermatofibroma is the classic dermoscopic pattern (pigment network and central white patch) [1]. The particularity of our observation is the dermoscopic description, not reported.


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Figure 1: Nodule of 1 cm of erythematous mole consistency in places and pigmented by others, well limited, with regular contours, base not infiltrated, resting on healthy skin.

 


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Figure 2: Dermoscopy, interspersed shiny white linear structures achieving a grid appearance, with the visualization of vessels in points at its crossed structures.

 


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Figure 1: Histology, spindle cell population, a fasciculate and storiform architecture with polymorphonuclear cells, eosinophils and lymphocytes.

 

References

1. Zaballos, P., Puig, S., Llambrich, A., & Malvehy, J. (2008). Dermoscopy of Dermatofibromas. Archives of Dermatology, 144(1). doi:10.1001/archdermatol.2007.8