MedRead Journal of Veterinary Science

Researcher psychology opens Animals physiology

Novel subgenotypes of bovine viral diarrhea virus based on 5’ UTR molecular epidemiology in cattle from huhhot of Inner mongolia autonomous region, China

Published on: 2020-04-05


Bovine viral diarrhea (BVD) causes high economic losses in the cattle population worldwide. Here, we present the results of an epidemiological survey for Bovine viral diarrhea virus (BVDV) in Northwest of China. In this study, a total of 167 samples were collected from the bovine farms and cattle slaughters for epidemiology nearby Huhhot in Inner Mongolia Autonomous Region during 2017 and 2018. Positive BVDV isolates were genotyped based on a comparison of gene sequences from their 5’untranslated regions (5’UTR). Results indicated that, out of 167 samples, 68 (40.72%) were BVDV-RNA-positive. 28 of them were sequenced and analyzed with 5’UTR and used for constructing phylogenetic tree. Phylogenetic analysis based on 5’UTR revealed that13 of the BVDV isolates belong to BVDV-1 and 15 belong to BVDV-2 genotype. Interesting, two novel BVDV-1 subgenotypes and one novel BVDV-2 subgenotype were found in present study. Therefore, the result of this study will be useful to understand epidemiology in Inner Mongolia Autonomous Region and allow producers to better protect their livestock.


Bovine viral diarrhea viruses; Epidemiology; 5’UTR; Novel Genotype