Evidence & Reproducibility Ledger: Methodological Audits & Updates
Rather than publishing daily medical news summaries that amplify single-study press releases, this ledger records structural methodological audits, guideline revisions, and long-term trial follow-ups that change how clinicians and patients interpret evidence.
The Med-Read.org Evidence & Reproducibility Ledger tracks major methodological updates in clinical trial reporting (such as the CONSORT 2025 statement), post-marketing survival follow-ups of accelerated drug approvals, new WHO environmental health dose-response cohorts, and additions to the 2019-2022 MedRead citation concordance.
2026 Editorial Monographs & Evidence Reviews
| Publication Date | Category | Monograph Title & Core Thesis | Primary Dossier Link |
|---|---|---|---|
| 2026-11-09 | MANIFESTO · ANALYSIS | When Everyone Can Download a Medical Paper at 2 AM, Why Nobody Teaches You to Read the Denominator Why we rebuilt med-read.org as a non-commercial clinical study appraisal desk and preserved the 2019-2022 WHO & Heriot-Watt cited monographs. |
Read Full Manifesto → |
| 2026-11-02 | COHORT AUDIT | Six Years After MedRead MS-946: Integrating Peri-Urban Noise Measurements with WHO 53 dB Lden Cardiovascular Models Connecting the 2020 Quetta acoustic survey with 2024-2026 European and Asian endothelial dysfunction cohorts. |
Open Noise Monograph → |
| 2026-10-25 | ENDPOINT AUDIT | Why Informative Censoring Makes Toxic Cancer Drugs Look Effective on Progression-Free Survival Curves How early toxicity dropouts distort Kaplan-Meier PFS estimates when Overall Survival remains flat. |
Open Oncology Ledger → |
Frequently Asked Methodological & Clinical Questions
Plain-language answers grounded in CONSORT, GRADE, WHO guidelines, and per-1,000 absolute outcome arithmetic.
How often is the Med-Read.org Evidence Ledger updated?
We update our core NNT tables and methodological dossiers whenever a major reporting standard (such as CONSORT, PRISMA, or GRADE) is revised, when mature Overall Survival data are published for previously surrogate-approved therapies, or when historical citations require concordance expansion.
How do you handle corrections if a calculation error is found?
Any arithmetic or bibliographic error reported to [email protected] is verified against the primary trial tables within 48 hours and logged transparently with the correction date.
Source: [email protected]